Pyrimidines And Derivatives
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Filtered Search Results
Medchemexpress LLC Methyl tetracosanoate | 2442-49-1 | MFCD00009351 | 250 MG
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Methyl tetracosanoate, also known as Methyl lignocerate, is a fatty acid methyl ester primarily recognized for its anti-diabetic activity. This compound has demonstrated the ability to increase glucose uptake in differentiated 3T3-L1 adipocytes and elevates GLUT4 mRNA expression.
- Increases glucose uptake on differentiated 3T3-L1 adipocytes
- Elevates GLUT4 mRNA expression
- Purity of 98.0%
- Solid appearance
- White to off-white color
- Stable for 3 years at room temperature (solid form)
- Solutions stable for 2 years at -80°C or 1 year at -20°C
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Medchemexpress LLC AC 187 | 151804-77-2 | 98.9% | 2890.21 | 10 MG
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AC 187 is a potent and orally active amylin receptor antagonist. It demonstrates high selectivity for the amylin receptor compared to calcitonin and CGRP receptors. This compound exhibits neuroprotective effects by blocking amyloidβ protein (Aβ)-induced neurotoxicity and improving neuronal survival.
- Potent and orally active amylin receptor antagonist
- High selectivity for the amylin receptor
- Exhibits neuroprotective effects
- Blocks amyloidβ protein (Aβ)-induced neurotoxicity
- Improves neuronal survival
- Attenuates activation of caspases mediating Aβ-induced apoptotic cell death
- Increases glucagon concentration
- Accelerates gastric emptying of liquids
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Medchemexpress LLC Ethyl mycophenolate | 32483-51-5 | MFCD29079197 | >98.0% | C19H24O6 | 10MG
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Ethyl mycophenolate is a metabolite and potential impurity of mycophenolic acid, supplied as a purified analytical reference standard for research use. It is intended for impurity profiling, method development, and verification of synthetic and formulation processes.
- High purity for analytical reference and method validation.
- Identity confirmed by CAS and molecular data for traceability.
- Available in small milligram quantities for precise assays.
- Suitable for impurity profiling and stability studies.
- Stable solid form for straightforward storage and handling.
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Medchemexpress LLC Ethyl docos-13-enoat 50g
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Ethyl docos-13-enoate is a colorless or pale yellow liquid with a sweet floral aroma used as a flavoring agent in the food industry and as a flavor enhancer in perfumes and colognes It is also found in some vegetable oils and is used as a surfactant and emulsifier in personal care products Ethyl docos-13-enoate is a versatile compound used in various industries due to its pleasant odor and ability to mix ingredients together
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Medchemexpress LLC Cis-epoxysuccinic acid | 16533-72-5 | MFCD00191645 | >97.0% | 132.07 | C4H4O5 | 100MG
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cis-Epoxysuccinic acid is a research-grade small molecule that acts as a succinate receptor (SUCNR1/GPR91) agonist. It is supplied as a white to off-white solid with molecular formula C4H4O5 and molecular weight 132.07, typically offered at >97.0% purity for laboratory use. Reported activity includes inhibition of cAMP with an EC50 of 2.7 μM. Store protected from light at 4°C; in solvent keep at -80°C for long-term storage.
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Medchemexpress LLC 5-(Piperazin-1-yl)isoquinoline hydrochloride | 209733-17-5 | 99.6% | 249.74 | 500 MG
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5-(Piperazin-1-yl)isoquinoline hydrochloride is a chemical compound from MedChemExpress, identified as a drug intermediate. This product is characterized by its yellow to orange solid appearance.
- Consistent with structure based on 1H NMR Spectrum and LCMS
- Purity of 99.6% as determined by LCMS
- Molecular formula: C13H16CIN3
- Molecular weight: 249.74
- Store at 4°C, sealed, away from moisture
- In solvent, store at -80°C for 6 months or -20°C for 1 month, sealed and away from moisture
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Medchemexpress LLC Hexythiazox | 78587-05-0 | 99.6% | 250 MG
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Hexythiazox is a selective acaricide with ovicidal, larvicidal, and nymphicidal activities. It is widely used for the chemical control of mites on cotton, fruits, and vegetables. This product is harmless to mammals and does not affect beneficial insects and predators of mites.
- Selective acaricide.
- Exhibits ovicidal activity.
- Exhibits larvicidal activity.
- Exhibits nymphicidal activity.
- Widely used for mite control on cotton, fruits, and vegetables.
- Harmless to mammals.
- No effect on beneficial insects and predators of mites.
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Medchemexpress LLC Sulfamethoxypyridazine | 80-35-3 | 99.9% | 250 MG
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Sulfamethoxypyridazine is a long-acting sulfonamide antibiotic primarily used for the treatment of Dermatitis herpetiformis. It is intended for research use only and not for sale to patients. This compound is available in solid form and is stable under recommended storage conditions, making it suitable for various laboratory applications.
- Used for treatment of dermatitis herpetiformis
- Long-acting sulfonamide antibiotic
- Intended for research use only
- Stable under recommended storage conditions
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Medchemexpress LLC Mitiglinide calcium | 145525-41-3 | 98.8% | 334.44 | 250 MG
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Mitiglinide calcium, an insulinotropic agent, is an ATP-sensitive K+ (KATP) channel antagonist. It is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell KATP channel) and can be used for the research of type 2 diabetes.
- Inhibits Kir6.2/SUR1 channel currents in a dose-dependent manner (IC50 value, 100 nM) in COS-1 cells.
- Suppresses the increase in plasma glucose levels after a meal load and the area under the curve for plasma glucose levels (AUCglucose).
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Medchemexpress LLC Ethyl 7-bromoheptanoate | 29823-18-5 | 237.13 | 25 G
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Ethyl 7-bromoheptanoate is a key intermediate and alkylating agent used in the synthesis of other active compounds. It can be utilized in the synthesis of prostaglandins and their analogues, and can react with quinazoline derivatives containing hydroxyl groups to introduce ester group-containing side chains.
- Key intermediate
- Alkylating agent
- Used in the synthesis of prostaglandins and their analogues
- Can introduce ester group-containing side chains to quinazoline derivatives
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Medchemexpress LLC DL-Isocitric acid trisodium salt | 1637-73-6 | 98.0% | 258.07 | 500 MG
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DL-Isocitric acid trisodium salt is an endogenous metabolite and an intermediate product in the citric acid cycle. It can be used as a marker for determining the composition of isocitrates in fruit products. It can also inhibit the hypertrophy of cardiomyocytes in vitro.
- Endogenous metabolite
- Intermediate product in the citric acid cycle
- Can be used as a marker for determining the composition of isocitrates in fruit products
- Can inhibit the hypertrophy of cardiomyocytes in vitro
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Medchemexpress LLC Dabigatran ethyl ester hydrochloride | 211914-50-0 | 99.4% | C27H30ClN7O3 | 1 ML
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Dabigatran ethyl ester hydrochloride is a potent inhibitor of ribosyldihydronicotinamide dehydrogenase (NQO2) with an IC50 value of 0.8 μM. It also functions as a thrombin inhibitor. The ethyl ester group enhances interaction with hydrophobic amino acids, contributing to its higher affinity for both thrombin and NQO2 compared to Dabigatran. This compound is a selective, reversible, and potent thrombin inhibitor, orally available as the prodrug, dabigatran etexilate.
- Potent inhibitor of ribosyldihydronicotinamide dehydrogenase (NQO2)
- Thrombin inhibitor
- Higher affinity for thrombin and NQO2 compared to Dabigatran
- Selective and reversible thrombin inhibitor
- Orally available as the prodrug dabigatran etexilate
- For research use only
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Medchemexpress LLC Benzonitrile, 4,4'-(hydroxymethylene)bis- | 134521-16-7 | 234.25 | 1 ML
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CGP 44 645 is the methanol metabolite of Letrozole. It serves as a molecular indicator for evaluating the metabolic kinetics of Letrozole in microsomes in vitro, with levels in rat liver microsomes potentially being sex-specific.
- For research use only
- Metabolic enzyme/protease drug metabolite
- Molecular indicator for evaluating metabolic kinetics in microsomes in vitro
- Soluble in DMSO (≥ 200 mg/mL)
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Medchemexpress LLC N2-methylguanosine | 2140-77-4 | MFCD00057039 | 98.1% | 297.27 g/mol | C11H15N5O5 | 5 MG
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N2-methylguanosine is a methylated nucleoside present in rRNA and tRNA, supplied as a research-grade analytical standard in powder form. It is intended for biochemical and analytical applications and can influence RNA structure and stability.
- Provided as a powder for research use only.
- High purity (~98.1%).
- Molecular formula C11H15N5O5; molecular weight 297.27 g/mol.
- Soluble in DMSO (≈7.69 mg/mL with ultrasonic).
- Recommended storage -20°C (3 years) or 4°C (2 years).
- Available in small pack sizes suitable for analytical use.
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Medchemexpress LLC Pyrimidine-4-carboxylic acid | 31462-59-6 | 124.10 | 10 G
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Pyrimidine-4-carboxylic acid is a biochemical reagent suitable for diverse life science research. It functions as both a biological material and an organic compound, and is also an important synthetic intermediate in pharmaceutical synthesis.
- Biological material
- Organic compound
- Useful for life science related research
- Synthetic intermediate for pharmaceutical synthesis
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